The UK National Institute for Health and Care Excellence (NICE) issued guidelines for managing endometriosis in 2017. Treatment can be with oral medication or with surgery and depends on the primary symptoms and importantly, the patient’s desire for pregnancy. For managing pain, simple pain-killers can be effective and are often used as a first-line option. Since endometriosis is hormone-dependent, other treatment options include hormonal manipulation, for instance, with the combined oral contraceptive pill. A new drug recently approved by the US FDA known as Elagolix (marketed as Orilissa), shows promise in treating endometriosis symptoms. The surgical option involves laparoscopic surgery, which can confirm the diagnosis, map the extent of the disease and allow deposits and chocolate cysts to be cut away.